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Agenda

Thursday, March 1

7:30-9:00 Arrival & Registration
Continental Breakfast
9:00-9:05 Welcome and Program Overview
9:05-9:15 Brian Kennedy – Buck Institute for Research on Aging
Introduction to Buck Institute for Research on Aging
Session One Chair: Thomas A. Rando, MD, PhD – Stanford University School of Medicine
9:15-9:45 George Q. Daley, MD, PhD – HHMI/Children’s Hospital Boston
Lin28 in Disease and Development
9:45-10:15 Lisa M. Ellerby, PhD – Buck Institute for Research on Aging
Designing Stem Cells in Huntington Disease
10:15-10:45 Paul Robson, PhD - Genome Institute of Singapore
The Potency of Human Embryonic Stem Cells 
10:45-11:00 Break
11:00-11:30 Arturo Alvarez-Buylla, PhD – UCSF School of Medicine
Neural Stem Cells in the Adult Brain
11:30-12:00 Rachelle J. Sells Galvin, PhD – Eli Lilly and Company
Application of Stem Cell Technologies to Drug Development
12:00-12:30 Anne Brunet, PhD – Stanford University
Neural Stem Cell Aging
12:30-1:30 Buffet Lunch
Session Two Chair: Victoria V. Lunyak, PhD – Buck Institute for Research on Aging
1:30-2:00 Michael Geoffrey Rosenfeld, MD – UCSD
ncRNAs in Developmental and Regulated Gene Transcriptional Programs
 
2:00-2:30 Arvind Ramanathan, PhD – Buck Institute for Research on Aging
Stem Cell Metabolism: Using Metabolomics to Study the Role of Aryl Hydrocarbon Receptors
2:30-3:00 Juan Carlos Izpisύa Belmonte, PhD – The Salk Institute for Biological Studies
Generation and Correction of Laminopathy-Associated LMNA Mutations in Patient Specific iPSCs
3:00-3:15 Break
3:15-3:45 Deepak Lamba, MBBS, MS, PhD – Buck Institute for Research on Aging
Human Pluripotent Stem Cells:  Applications for Retinal Diseases
3:45-4:15 John Crispino, PhD – Northwestern University
Aberrant Hematopoiesis in Down Syndrome
4:15-4:45 Susan J. Fisher, PhD – UCSF
Specifying a Human Embryonic or a Trophoblast Fate
4:45-6:00 Wine and Poster Session
6:00-7:30 Dinner at the Buck Institute
Keynote Chair: Julie Andersen, PhD – Buck Institute for Research on Aging
7:30-8:20 Keynote Address
Ole Isacson, MD – McLean Hospital/Harvard Medical School
New Medicines and Treatments for Parkinson's Disease Patients From Stem and iPS Cells

Friday, March 2

8:30-9:00 Registration
Continental Breakfast
Session Three Chair: Lisa M. Ellerby, PhD – Buck Institute for Research on Aging
9:05-9:35 Thomas A. Rando, MD, PhD – Stanford University School of Medicine
Epigenetic Mechanisms of Stem Cell Aging and Rejuvenation
9:35-10:15 TBA 
10:15-10:35 Jing-Dong Jackie Han, PhD – Chinese Academy of Science
In Search for the Regulatory Network of Aging
10:35-11:05 Victoria V. Lunyak, PhD – Buck Institute for Research on Aging
Epigenetic Regulations in Human Mesenchymal Stem Cell Aging
11:05-11:15 Break
11:15-11:45 Leanne Jones, PhD – UCSD
Maintenance of Niche Function and Tissue Homeostasis During Aging
11:45-12:15 Heinrich Jasper, PhD – University of Rochester
Control of Proliferative Plasticity in the Adult Intestine of Drosophila
12:15-12:45 Irina Conboy, PhD – UC Berkeley
Slowing Down the Rate of Aging Through Stem Cell Engineering
12:45-1:30 Buffet Lunch
Session Four

CIRM and NIH Roadmap to Parkinson Disease Study
Chair: Xianmin Zeng, PhD – Buck Institute for Research on Aging

1:30-2:00 Ellen Feigal, MD – CIRM
CIRM Overview
2:00-2:30 Arnold R. Kriegstein MD, PhD – UCSF School of Medicine
Neural Stem and Progenitor Cells in Human Cortical Development and Evolution
2:30-3:00 Johannes Schwarz, MD – Technical University of Munich
Fetal Human Neural Progenitor Cells as a Model to Study Brain Development in Vitro 
3:00-3:30 Kwang-Soo Kim, PhD – McLean Hospital/Harvard Medical School
Protein-Based iPS Cells for Regenerative Medicine
3:30-3:45  Break
3:45-4:15 Xianmin Zeng, PhD – Buck Institute for Research on Aging
Parkinson's Disease: ESC/iPSC-derived Dopaminergic Neurons for Therapy and Screening
4:15-4:45 Russell Lonser, MD – NIH Clinical Center, NINDS
Clinical Trial at the NIH Clinical Center for Neurological Disorders
4:45-5:15  Joel M. Gottesfeld, PhD – The Scripps Research Institute
Modeling Neurodegenerative Diseases with iPSC-derived Neurons and Screens for Small Molecule Therapeutics
5:15-5:45 Mahendra Rao, MD, PhD - NIH
Stem Cells for Screening and Therapy - NIH CRM Efforts